12/2018. Allergoids coupled to mannan. A review
A review has been published in Allergo Journal International about novel vaccines targeting dendritic cells based on the conjugation of allergoids to nonoxidized mannan. These represent a next generation of allergy vaccines developed by INMUNOTEK.
The publication reviews these glycoconjugates in terms of their ability to be recognized by the antigen-presenting cells, their immunomodulatory properties and clinical development.
Allergo Journal International is the official Journal of the German Society for Allergology and Clinical Immunology (DGAKI) and of the Medical Association of German Allergologists [Ärzteverband der Deutschen Allergologen (ÄDA)]. This review has been highlighted in the German edition of the journal.
Related Bibliography:
Manzano AI, Javier Cañada F, Cases B, Sirvent S, Soria I, Palomares O, Fernández-Caldas E, Casanovas M, Jiménez-Barbero J, Subiza JL. Glycoconj J. 2016 Feb;33(1):93-101. doi: 10.1007/s10719-015-9640-4. Epub 2015 Nov 25.
Sirvent S, Soria I, Cirauqui C, Cases B, Manzano AI, Diez-Rivero CM, Reche PA, López-Relaño J, Martínez-Naves E, Cañada FJ, Jiménez-Barbero J, Subiza J, Casanovas M, Fernández-Caldas E, Subiza JL, Palomares O. J Allergy Clin Immunol. 2016 Aug;138(2):558-567.e11. doi: 10.1016/j.jaci.2016.02.029. Epub 2016 Apr 13
Dendritic cell targeting with C-type lectins for improvement of allergen immunotherapy.
Schülke S, Vieths S. J Allergy Clin Immunol. 2016 Aug;138(2):568-70. doi: 10.1016/j.jaci.2016.06.006. Epub 2016 Jun 23.
Das M, Galeotti C, Stephen-Victor E, Karnam A, Kaveri SV, Bayry J. J Allergy Clin Immunol. 2017 Apr;139(4):1403-1404.e1. doi: 10.1016/j.jaci.2016.09.062. Epub 2017 Jan 11.
Soria I, Alvarez J, Manzano AI, López-Relaño J, Cases B, Mas-Fontao A, Cañada FJ, Fernández-Caldas E, Casanovas M, Jiménez-Barbero J, Palomares O, Viñals-Flórez LM, Subiza JL. Vet Immunol Immunopathol. 2017 Aug;190:65-72. doi: 10.1016/j.vetimm.2017.07.004. Epub 2017 Jul 23.
Soria I, López-Relaño J, Viñuela M, Tudela JI, Angelina A, Benito-Villalvilla C, Díez-Rivero CM, Cases B, Manzano AI, Fernández-Caldas E, Casanovas M, Palomares O, Subiza JL. Allergy. 2018 Apr;73(4):875-884. doi: 10.1111/all.13396. Epub 2018 Jan 31
González JL, Zalve V, Fernández-Caldas E, Cases B, Subiza JL, Casanovas M. Vet Dermatol. 2018 Oct;29(5):449-e152. doi: 10.1111/vde.12679.
Novel vaccines targeting dendritic cells by coupling allergoids to mannan.
Benito-Villalvilla C, Soria I, Subiza JL, Palomares O. Allergo J Int (2018) 27:256-262. https://doi.org/10.1007/s40629-018-0069-8
Dendritische Zellen unterstützen Allergieimpfung
Leiner P, Jakob T. Allergo J (2018) Dec;27(8):14-15. https://doi.org/10.1007/s15007-018-1761-1