The research study on the effect of aluminum in the new allergoid-mannan conjugates carried out at the Complutense University of Madrid and INMUNOTEK published in Allergy, has been selected to be included in the opening issue of the Virtual Issue collection, aimed to promote the dissemination of outstanding studies.
Allergy to mosquitoes and mites is common in certain geographic areas and both have important allergens such as tropomyosin that can lead to cross-reactions between them. A study has been published in Clinical Experimental Allergy which shows that the mosquito Aedes aegypti and the mite Dermatophagoides pteronyssinus share regions in their tropomyosin that justify the cross-response of antibodies and T cells.
A new study on novel allergoid-mannan conjugates developed by INMUNOTEK has been published in Veterinary Immunology Immunopathology. In this study the glycoconjugates were performed with mite allergens (Dermatophagoides farinae) that sensitize dogs suffering canine atopic dermatitis. Antibodies and cell responses were assayed. The results indicated that these glycoconjugates are hypoallergenic and better captured by the cells involved in antigen presentation (dendritic cells)
