The research study on the effect of aluminum in the new allergoid-mannan conjugates carried out at the Complutense University of Madrid and INMUNOTEK published in Allergy, has been selected to be included in the opening issue of the Virtual Issue collection, aimed to promote the dissemination of outstanding studies.
Financial Times features INMUNOTEK as an example of a Spanish company with strong growth along the years even in unfavorable situations. According to the economic newspaper, the strength of these companies is based on their commitment to innovation and competitiveness. This allows to focus its productive activity towards foreign markets, have a sustained growth and create employment.
INMUNOTEK has been awarded as the Best SME of the Year 2019 by CEPYME (Spanish Confederation of Small and Medium-Sized Enterprises). This award recognizes Business Excellence under the criteria of business activity, innovation, internationalization and job creation. The award ceremony was chaired by the Spanish Minister of Economy and Business, Nadia Calviño, the President of CEPYME, Gerardo Cuerva and the CEO of Santander Bank, Rami Aboukhair, as sponsor of the award.
A recent publication in BMC Infectious Diseases journal indicates that UROMUNE decreases the recurrence of urinary tract infections. The study, conducted on a total of 784 patients in the hospitals of Mataró and Moisés Broggi (Barcelona) between 2011-2017, concludes that treatment with UROMUNE was highly effective to reduce the number of episodes of urinary tract infections at three and six months of follow-up. UROMUNE is a polybacterial mucosal vaccine developed by INMUNOTEK that is administered by a sublingual spray.
The effect of aluminum hydroxide on the tolerogenic properties of dendritic cells induced by allergoids coupled to mannan has been published in Allergy with the title “Alum impairs tolerogenic properties induced by allergoid-mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs”. The study has been carried out at the School of Chemistry of the Complutense University of Madrid with the collaboration of INMUNOTEK.
Within the Summer Courses of El Escorial organized by the Complutense University of Madrid, the one entitled “Trained immunity-based vaccines: the innate immune memory working towards antiinfectious immunotherapy” was held in Madrid during 11-12th of July under the direction of Dr. Silvia Sánchez Ramón (Immunology, San Carlos Clinical Hospital, Madrid) and Dr. Laura Conejero Hall (INMUNOTEK), Scientific Secretariat. The course, sponsored by INMUNOTEK, has combined basic aspects of the mechanisms of action of trained immunity, with the clinical outcome in recurrent respiratory and urinary tract infections.
Allergy to mosquitoes and mites is common in certain geographic areas and both have important allergens such as tropomyosin that can lead to cross-reactions between them. A study has been published in Clinical Experimental Allergy which shows that the mosquito Aedes aegypti and the mite Dermatophagoides pteronyssinus share regions in their tropomyosin that justify the cross-response of antibodies and T cells.
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