The Journal of Allergy and Clinical Immunology highlights in its June issue, section “News Beyond Our Pages”, the results published in AJRCCM (American Journal of Respiratory and Critical Care Medicine) with MV130, a sublingual preparation developed and manufactured by INMUNOTEK. The study, conducted in young children with recurrent bronchiolitis, demonstrates the efficacy of bacterial immunotherapy with MV130 in the reduction and duration of these episodes.
“Viral Outbreaks”, new book by IntechOpen, includes a chapter on trained immunity-based vaccines (TIbVs) with the participation of INMUNOTEK. These are broad-spectrum vaccines that could play an important role in temporarily protecting vulnerable people from dangerous viruses in the absence of effective specific vaccines.
A scoring proposal that combines symptoms and medication for the monitoring of allergic asthma in immunotherapy treatments is published in the International Archives of Allergy and Immunology. This proposal, developed by INMUNOTEK, facilitates the evaluation of the efficacy of immunotherapy in clinical trials.
According to research published in Frontiers in Immunology, the response to Candida albicans is enhanced and improved in combination with MV140 (Uromune). Recurrent vulvovaginal candidiasis is a common infection. Prevention measures and treatments are still limited. It is often associated with urinary tract infections as a consequence of antibiotic treatment. Uromune is a bacterial vaccine used to prevent recurrent urinary infections. In this experimental study it is demonstrated how the combination of MV140 with Candida albicans enhances the response against this fungus, favoring the specific and non-specific cellular response, as well as the antibody response.
Frontiers in Immunology publishes a study on the effect of MV130 (Bactek) on mesenchymal stem cells. These cells are acquiring a leading role not only for their differentiation capacity but also for their emerging immunomodulatory activity. Mesenchymal stem cells can take up the bacteria contained in MV130 and modify their functionality towards pro and anti-inflammatory responses in a controlled sequential way.
Peach tree pollen can be the cause of allergic rhinitis and asthma in exposed workers according to a paper published in Occupational and Environmental Medicine. Pru p 9 is identified as one of the relevant allergens and peach tree pollen is described as a cause of occupational allergy not previously described. The study opens the possibility of this type of allergy in workers with high exposure to entomophilous pollinating flowers, whose pollen has not been considered clinically relevant to date.
The Spanish Ministry of Science, Innovation and Universities has awarded INMUNOTEK the National Innovation Award 2019. This price, the highest award granted in Spain to distinguish companies that make innovation their main business growth strategy, is endowed with 30,000 euros and has been granted to INMUNOTEK in the category of “Small and Medium-Sized Enterprise”.
The XXII Botanical Identification Seminar Day “Eliseo Subiza” was dedicated to the olive tree and took place in Toledo. This initiative of the Hospital Virgen del Valle (Toledo) has the collaboration of INMUNOTEK and is aimed to perform a botanical training of young allergists in main local allergenic plants. Through field trips with botanical experts and aerobiological lectures, each year is dedicated to special plant. The olive tree is a tree of great allergological interest as a cause of pollinosis in Spain since its pollen is very allergenic and affects a large number of patients.
INMUNOTEK revalidates its Innovative SME stamp issued by the Spanish Government at the Directorate General for Innovation and Competitiveness of the Ministry of Economy. This stamp was granted to INMUNOTEK in 2015.
A recent study with UROMUNE (MV140) published in the British Journal of Urology International demonstrates its efficacy in the treatment of recurrent urinary tract infections. This condition has a considerable morbidity worldwide and requires the continued use of antibiotics.