Alum impairs the tolerogenic effects of allergoids coupled to mannan

October 2019

The effect of aluminum hydroxide on the tolerogenic properties of dendritic cells induced by allergoids coupled to mannan has been published in Allergy with the title "Alum impairs tolerogenic properties induced by allergoid-mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs". The study has been carried out at the School of Chemistry of the Complutense University of Madrid with the collaboration of INMUNOTEK.
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Trained Immunity-based Vaccines in El Escorial Summer Courses

July 2019

Within the Summer Courses of El Escorial organized by the Complutense University of Madrid, the one entitled "Trained immunity-based vaccines: the innate immune memory working towards  antiinfectious immunotherapy" was held in Madrid during 11-12th of July under the direction of Dr. Silvia Sánchez Ramón (Immunology, San Carlos Clinical Hospital, Madrid) and Dr. Laura Conejero Hall (INMUNOTEK), Scientific Secretariat. The course, sponsored by INMUNOTEK, has combined basic aspects of the mechanisms of action of trained immunity, with the clinical outcome in recurrent respiratory and urinary tract infections.
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Immunomodulatory effect of oral epithelial cells

July 2019

Frontiers in Immunology publishes the article "Human Oral Epithelial Cells Impair Bacteria-Mediated Maturation of Dendritic Cells and Render T Cells Unresponsive to Stimulation". This research reveals the immunomodulation exerted by the epithelial cells of the oral cavity either on cells of innate immunity stimulated with bacteria and/or on cells (T lymphocytes) of adaptive immunity. The research carried out in the School of Medicine of the Complutense University of Madrid has had the participation of INMUNOTEK.
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The olive tree protagonist in the "Eliseo Subiza" Botanical Day

May 2019

The XXII Botanical Identification Seminar Day "Eliseo Subiza" was dedicated to the olive tree and took place in Toledo. This initiative of the Hospital Virgen del Valle (Toledo) has the collaboration of INMUNOTEK and is aimed to perform a botanical training of young allergists in main local allergenic plants. Through field trips with botanical experts and aerobiological lectures, each year is dedicated to special plant. The olive tree is a tree of great allergological interest as a cause of pollinosis in Spain since its pollen is very allergenic and affects a large number of patients.
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Tonsil surgery is reduced with Bactek-MV130

Amigadalitis InmunologíaApril 2019

Human Vaccines & Immunotherapeutics publishes a study showing that Bactek-MV130, in combination with antibiotics, reduces the need of tonsillectomy in adult patients with recurrent tonsillitis. The study conducted in two hospitals in Asturias - Spain by doctors Luis-Amando García González and Federico Arrutia Díez compares patients treated only with antibiotics or with antibiotics plus Bactek-MV130.
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Premios Inmunotek LogoJanuary 2019

The INMUNOTEK Prizes were awarded at the event held during the 9th Scientific Conference of the SICAM (Community Immunology Society of Madrid) held in Madrid on 18th January. These awards are now in their fourth call and aim to recognize the best clinical and basic research presented during this Conference.
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TIbV - Trained Immunity-based Vaccines

January 2019

Frontiers in Immunology publishes the article entitled "Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations" in the Topic Research issue of Reverse Vaccinology, within the section of Vaccines and Molecular Therapeutics. In this review, the potential of "Trained Immunity" in the development of new vaccines (TIbV) and their possible clinical applications are outlined. The article is co-authored by members of INMUNOTEK among leading experts in the field.
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Allergoids coupled to mannan. A review

vacunas alergiaDecember 2018

Novel glycoconjugates of allergoids coupled to mannan for a next generation of allergy vaccines. Allergo Journal International publishes a review about the development and main features of these novel vaccines targeting dendritic cells.
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iGEM 2018 competition

iGEM 2018November 2018

The iGEM-Madrid team, sponsored by INMUNOTEK, has been awarded in the international competition held in Boston (iGEM 2018). The project "IoBT-Internet of Bio-Things" is an automatic system where engineering, communications and biosensors of the latest generation based on aptamers are integrated to detect allergen contamination in the air of the cities. The iGEM competition (International Genetically Engineered Machine) aims to encourage students and recent graduates to design bioengineering prototypes that provide imaginative solutions to real needs and therefore with commercial interest.
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Novel allergoid-mannan vaccine in veterinary medicine

PerroOctober 2018

Veterinary Dermatology has published a clinical trial with dogs suffering atopic dermatitis with a novel allergoid-mannan glycoconjugate vaccine developed by INMUNOTEK.
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