A nasal irrigation liquid must be a tamponated saline solution free of substances that could damage sensitive nasal mucosa as those preservatives found in table salt. Non-tamponated saline (physiological serum) could have a negative effect on the nasal cilia. A number of tamponated solutions have been researched and the Locke-Ringer solution is the best for the ciliary function and the nasal mucosa as it contains all the ions necessary to preserve said function.