08/2023. Cross-reactivity between bacteria and viruses

Frontiers in Immunology publishes an interesting study investigating the potential of bacteria to generate antigen-specific viral responses.

The results show that bacteria share peptide sequences with respiratory viruses (rhinoviruses, syncytial viruses, influenza and SARS-CoV-2). The shared peptides were shown to be distinct between different bacteria, so that bacterial combination increases the spectrum of cross-reactivity. Thus, the polybacterial preparation MV130 has been shown to have the potential to induce both cellular (CD4/CD8) and humoral (antibody) responses against influenza virus.

The study has been performed in silico at the Complutense University of Madrid under the direction of Prof. Pedro Reche with the collaboration of INMUNOTEK.

MV130 is a sublingual preparation developed by INMUNOTEK for the prevention of respiratory infections.

More info on MV130 here.